{"id":1815,"date":"2021-06-28T16:05:53","date_gmt":"2021-06-28T14:05:53","guid":{"rendered":"http:\/\/www.lampugnanifarmaceutici.it\/our-publications\/boswellia-resin-extract-and-propolis-for-prostatitis-symptoms\/"},"modified":"2021-06-28T16:56:44","modified_gmt":"2021-06-28T14:56:44","slug":"boswellia-resin-extract-and-propolis-for-prostatitis-symptoms","status":"publish","type":"post","link":"https:\/\/www.lampugnanifarmaceutici.it\/en\/our-publications\/boswellia-resin-extract-and-propolis-for-prostatitis-symptoms\/","title":{"rendered":"Boswellia resin extract and propolis for prostatitis symptoms"},"content":{"rendered":"

[vc_row][vc_column width=”1\/4″][vc_empty_space height=”20px”][vc_single_image image=”599″ img_size=”91×150″ alignment=”center”][vc_column_text]<\/p>\n

LAMPUGNANI
\nFARMACEUTICI<\/h1>\n

[\/vc_column_text][vc_empty_space height=”5px”][\/vc_column][vc_column width=”3\/4″][vc_message message_box_color=”peacoc” icon_fontawesome=”fa fa-info”]The association of Boswellia resin extract and propolis derived polyphenols can improve quality of life in patients affected by prostatitis-like symptoms<\/strong>[\/vc_message][vc_message message_box_color=”chino” icon_fontawesome=”fa fa-home”]EDITION<\/strong>: Archivio Italiano di Urologia e Andrologia, anno 2019, volume 91, n. 4 , pubblicato il 14 gennaio 2020[\/vc_message][vc_message message_box_color=”juicy_pink” icon_fontawesome=”fa fa-pencil”]AUTHOR<\/strong>: Mattia Sibona
\nDipartimento di Urologia, A.O.U. Citt\u00e0 della Salute e della Scienza di Torino, Ospedale le Molinette, Universit\u00e0 di Torino, Italia.[\/vc_message][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text]DOI <\/strong> https:\/\/doi.org\/10.4081\/aiua.2019.4.251<\/a><\/p>\n

Mattia Sibona<\/strong> *
\nDepartment of Urology, Department of Surgical Sciences, A.O.U. Citt\u00e0 della Salute e della Scienza di Torino, Molinette Hospital, University of Turin, Italy.
\nPaolo Destefanis<\/strong>
\nDepartment of Urology, Department of Surgical Sciences, A.O.U. Citt\u00e0 della Salute e della Scienza di Torino, Molinette Hospital, University of Turin, Italy.
\nMarco Agnello<\/strong>
\nDepartment of Urology, Department of Surgical Sciences, A.O.U. Citt\u00e0 della Salute e della Scienza di Torino, Molinette Hospital, University of Turin, Italy.
\nBeatrice Lillaz<\/strong>
\nDepartment of Urology, Department of Surgical Sciences, A.O.U. Citt\u00e0 della Salute e della Scienza di Torino, Molinette Hospital, University of Turin, Italy.
\nMattia Giuliano<\/strong>
\nDepartment of Urology, Department of Surgical Sciences, A.O.U. Citt\u00e0 della Salute e della Scienza di Torino, Molinette Hospital, University of Turin, Italy.
\nTommaso Cai<\/strong>
\nDepartment of Urology, Santa Chiara Regional Hospital, Trento, Italy.
\nPaolo Gontero<\/strong>
\nDepartment of Urology, Department of Surgical Sciences, A.O.U. Citt\u00e0 della Salute e della Scienza di Torino, Molinette Hospital, University of Turin, Italy.
\n(*) Corresponding Author:
\nMattia Sibona<\/strong> | mattia.sibona@gmail.com
\n[\/vc_column_text][vc_column_text]<\/p>\n

Abstract<\/h4>\n

Objectives<\/strong>: Chronic prostatitis syndrome is a bothering and poorly understood condition. Many patients report genitourinary pain and Lower Urinary Tract Symptoms as a main complaint. Many different pharmacological or behavioural therapies are prescribed in daily clinical practice, but efficacy data are still lacking. The aim of our study was to test the efficacy and safety of a transrectal delivered association of Boswellia resin extract and propolis derived polyphenols for the relief of prostatitis – like symptoms.<\/p>\n

Materials and methods<\/strong>: Patients affected by chronic\/recurrent prostatitis – like symptoms were prospectively enrolled in our study from December, 2016 to December, 2018. Patients were screened at baseline through clinical examination and validated questionnaires administration: Chronic Prostatitis Symptom Index (CPSI), International Prostate Symptom Score (IPSS), International Index of Erectile Function (IIEF). Inclusion criteria were: age \u2265 18; prostatitis symptoms persisting for at least 3 of the last 6 months; CPSI pain domain score \u2265 5; previous negative Meares-Stamey test. Treatment consisted on the administration of 1 suppository containing Boswellia resin extract and propolis derived polyphenols, once a day for 20 days. The primary endpoint of the study was the improvement of quality of life after treatment, defined by a reduction of \u2265 2 points, or \u2265 25%, of mean CPSI pain domain score, compared to baseline. Secondary endpoints were the improvement of post-treatment CPSI total score and the analysis of treatment – related adverse events. All patients were re-evaluated 1 month after treatment.<\/p>\n

Results<\/strong>: 40 patients were enrolled in our study. Median age (Inter – Quartile Range IQR) was 51.5 (41.5-63.2) years. Mean baseline CPSI scores were: 22.15 (total score), 9.67 (pain domain), 5.15 (micturition domain) and 7.35 (quality of life domain), respectively. No significant adverse events were reported. At 1 month follow-up, CPSI scores appeared modified as follows: 16.40 (total score, p = 0.001); 6.92 (pain domain; p = 0.001; 4.02 (micturition domain, p = 0.09); 5.45 (quality of life domain, p = 0.002). Mean CPSI pain domain score reduction was -2.75 points (-28.5%). Mean CPSI total score reduction was -5.75 points (-26%).<\/p>\n

Conclusions<\/strong>: The association of Boswellia resin extract and propolis derived polyphenols can reduce genitourinary pain and then improve quality of life of men affected by bothersome prostatitis – like symptoms.[\/vc_column_text][vc_column_text]Published<\/strong>: Jan 14, 2020
\nOriginal Papers \u2013 Andrology
\nVol 91 No 4 (2019)<\/a>
\nArchivio Italiano di Urologia e Andrologia[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

EDITION: Archivio Italiano di Urologia e Andrologia
\nAUTHOR: Mattia Sibona<\/p>\n","protected":false},"author":1,"featured_media":1811,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[31],"tags":[],"class_list":["post-1815","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-our-publications"],"jetpack_featured_media_url":"https:\/\/www.lampugnanifarmaceutici.it\/wp-content\/uploads\/Lampugnani-icona-pubblicazioni-new.png","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.lampugnanifarmaceutici.it\/en\/wp-json\/wp\/v2\/posts\/1815","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lampugnanifarmaceutici.it\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.lampugnanifarmaceutici.it\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.lampugnanifarmaceutici.it\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lampugnanifarmaceutici.it\/en\/wp-json\/wp\/v2\/comments?post=1815"}],"version-history":[{"count":1,"href":"https:\/\/www.lampugnanifarmaceutici.it\/en\/wp-json\/wp\/v2\/posts\/1815\/revisions"}],"predecessor-version":[{"id":1816,"href":"https:\/\/www.lampugnanifarmaceutici.it\/en\/wp-json\/wp\/v2\/posts\/1815\/revisions\/1816"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.lampugnanifarmaceutici.it\/en\/wp-json\/wp\/v2\/media\/1811"}],"wp:attachment":[{"href":"https:\/\/www.lampugnanifarmaceutici.it\/en\/wp-json\/wp\/v2\/media?parent=1815"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.lampugnanifarmaceutici.it\/en\/wp-json\/wp\/v2\/categories?post=1815"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.lampugnanifarmaceutici.it\/en\/wp-json\/wp\/v2\/tags?post=1815"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}